Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07QBL
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| Drug Name |
PMID27539678-Compound-12
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| Drug Type |
Small molecular drug
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| Company |
AJINOMOTO CO., INC
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| Structure |
 |
Download2D MOL |
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| Formula |
C26H32N2O2
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| Canonical SMILES |
C1CCC(C1)OCC2=CC(=CC=C2)C3=CC4=C(C=C3)NC(=C4)CN5CCCC5CO
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| InChI |
1S/C26H32N2O2/c29-17-24-7-4-12-28(24)16-23-15-22-14-21(10-11-26(22)27-23)20-6-3-5-19(13-20)18-30-25-8-1-2-9-25/h3,5-6,10-11,13-15,24-25,27,29H,1-2,4,7-9,12,16-18H2/t24-/m1/s1
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| InChIKey |
GCKSLJXLYRTNCV-XMMPIXPASA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sphingosine kinase 1 (SPHK1) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Sphingosine kinase 1 (SPHK1) | Target's Patent Info | [1] | |
| BioCyc | Sphingosine and sphingosine-1-phosphate metabolism | |||
| KEGG Pathway | Sphingolipid metabolism | |||
| Metabolic pathways | ||||
| Calcium signaling pathway | ||||
| Sphingolipid signaling pathway | ||||
| VEGF signaling pathway | ||||
| Fc gamma R-mediated phagocytosis | ||||
| Tuberculosis | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Panther Pathway | Angiogenesis | |||
| VEGF signaling pathway | ||||
| Pathway Interaction Database | Fc-epsilon receptor I signaling in mast cells | |||
| Beta3 integrin cell surface interactions | ||||
| S1P1 pathway | ||||
| Sphingosine 1-phosphate (S1P) pathway | ||||
| PDGFR-beta signaling pathway | ||||
| Reactome | Sphingolipid de novo biosynthesis | |||
| VEGFR2 mediated cell proliferation | ||||
| WikiPathways | Signal Transduction of S1P Receptor | |||
| Protein folding | ||||
| Sphingolipid Metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Sphingosine kinase inhibitors: a review of patent literature (2006-2015).Expert Opin Ther Pat. 2016 Dec;26(12):1409-1416. | |||
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