Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07SDE
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| Former ID |
DIB006274
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| Drug Name |
Pranidipine
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| Synonyms |
Acalas; OPC-13340; OPC-13463
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| Drug Type |
Small molecular drug
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Terminated | [1] | |
| Company |
Otsuka Pharmaceutical Co Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C25H24N2O6
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| Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OCC=CC2=CC=CC=C2)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
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| InChI |
1S/C25H24N2O6/c1-16-21(24(28)32-3)23(19-12-7-13-20(15-19)27(30)31)22(17(2)26-16)25(29)33-14-8-11-18-9-5-4-6-10-18/h4-13,15,23,26H,14H2,1-3H3/b11-8+
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| InChIKey |
XTFPDGZNWTZCMF-DHZHZOJOSA-N
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| CAS Number |
CAS 99522-79-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Calcium channel unspecific (CaC) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000287) | |||
| REF 2 | Pranidipine, a new 1,4-dihydropyridine calcium channel blocker, enhances cyclic GMP-independent nitric oxide-induced relaxation of the rat aorta. Mol Cell Biochem. 1998 Jan;178(1-2):335-43. | |||
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