Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07TST
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| Former ID |
DNC010840
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| Drug Name |
4-(2-(Cyclohexylamino)ethyl)-1H-imidazole
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| Synonyms |
CHEMBL1096513; 4-(2-(Cyclohexylamino)ethyl)-1H-imidazole; BDBM50317872
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H19N3
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| Canonical SMILES |
C1CCC(CC1)NCCC2=CN=CN2
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| InChI |
1S/C11H19N3/c1-2-4-10(5-3-1)13-7-6-11-8-12-9-14-11/h8-10,13H,1-7H2,(H,12,14)
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| InChIKey |
OKJFYIHINPOKMF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Role of hydrophobic substituents on the terminal nitrogen of histamine in receptor binding and agonist activity: development of an orally active hi... J Med Chem. 2010 May 13;53(9):3840-4. | |||
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