Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07VYX
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| Former ID |
DNC007295
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| Drug Name |
4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate
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| Synonyms |
CHEMBL224828; 4-((+/-)-(1H-imidazol-1-yl)-(E)-methylretinoate; BDBM50158415; 4-(1-Imidazolyl)retinoic acid methyl ester
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C24H32N2O2
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| Canonical SMILES |
CC1=C(C(CCC1N2C=CN=C2)(C)C)C=CC(=CC=CC(=CC(=O)OC)C)C
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| InChI |
1S/C24H32N2O2/c1-18(8-7-9-19(2)16-23(27)28-6)10-11-21-20(3)22(12-13-24(21,4)5)26-15-14-25-17-26/h7-11,14-17,22H,12-13H2,1-6H3/b9-7+,11-10+,18-8+,19-16+
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| InChIKey |
LEOKNFOQHCUMCU-PFLBVIONSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cytochrome P450 26 (CYP26A1) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Retinol metabolism | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Retinol Metabolism | |||
| WikiPathways | Vitamin A and Carotenoid Metabolism | |||
| Metapathway biotransformation | ||||
| Oxidation by Cytochrome P450 | ||||
| Nuclear Receptors in Lipid Metabolism and Toxicity | ||||
| Adipogenesis | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and pros... J Med Chem. 2004 Dec 30;47(27):6716-29. | |||
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