Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07WEP
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| Former ID |
DAP000956
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| Drug Name |
Diazoxide
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| Synonyms |
Aroglycem; Diazossido; Diazoxido; Diazoxidum; Dizoxide; Eudemine; Hyperstat; Hypertonalum; Mutabase; Proglicem; Proglycem; Diazossido [DCIT]; Diazossido [Italian]; D 9035; SRG 95213; Sch 6783; Diazoxido [INN-Spanish]; Diazoxidum [INN-Latin]; Hyperstat (TN); SRG-95213; Sch-6783; Diazoxide [USAN:INN:BAN]; Diazoxide (JAN/USP/INN); 2H-1,2, 4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide; 2H-1,2,4-Benzothiadiazine, 7-chloro-3-methyl-, 1,1-dioxide; 7-Chloro-3-methyl-1lambda~4~,2,4-benzothiadiazin-1-ol 1-oxide; 7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide; 7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido; 7-Cloro-3-metil-2H-1,2,4-benzotiodiazina-1,1-diossido [Italian]; 7-chloro-3-methyl-4H-1
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Approved | [1], [2] | |
| Therapeutic Class |
Antihypertensive Agents
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| Structure |
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Download2D MOL |
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| Formula |
C8H7ClN2O2S
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| Canonical SMILES |
CC1=NS(=O)(=O)C2=C(N1)C=CC(=C2)Cl
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| InChI |
1S/C8H7ClN2O2S/c1-5-10-7-3-2-6(9)4-8(7)14(12,13)11-5/h2-4H,1H3,(H,10,11)
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| InChIKey |
GDLBFKVLRPITMI-UHFFFAOYSA-N
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| CAS Number |
CAS 364-98-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9164, 549108, 550870, 798334, 855807, 5349995, 6452039, 7847360, 7979064, 10321263, 10744184, 11111110, 11111111, 11113823, 11119917, 11120405, 11120893, 11121372, 11121852, 11147000, 11362441, 11365003, 11367565, 11370153, 11370154, 11371610, 11373166, 11374914, 11375727, 11466115, 11467235, 11485689, 11490551, 11493062, 14749339, 16616077, 17404967, 24277831, 24714736, 26613180, 26747146, 26747147, 26751995, 26751996, 29222166, 46386946, 46508027, 47216514, 47290866, 47290867
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| ChEBI ID |
CHEBI:4495
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| ADReCS Drug ID | BADD_D00649 | |||
| SuperDrug ATC ID |
C02DA01; V03AH01
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| SuperDrug CAS ID |
cas=000364987
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Modulator | [3] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 2409). | |||
| REF 2 | FDA Approved Drug Products from FDA Official Website. 2009. Application Number: (NDA) 016996. | |||
| REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. | |||
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