Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07WJU
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| Former ID |
DIB010886
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| Drug Name |
SUVN-911
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| Synonyms |
Alpha 4 beta 2 nicotinic acetylcholine receptor (nAChR) antagonist (depression), Suven
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| Indication | Major depressive disorder [ICD-11: 6A70.3; ICD-10: F32.2] | Phase 1 | [1] | |
| Company |
Suven Life Sciences Ltd
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Neuronal acetylcholine receptor beta-2 (CHRNB2) | Target Info | Antagonist | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Cholinergic synapse | ||||
| Nicotine addiction | ||||
| Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
| Nicotine pharmacodynamics pathway | ||||
| Reactome | Highly sodium permeable acetylcholine nicotinic receptors | |||
| Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | ||||
| Highly calcium permeable nicotinic acetylcholine receptors | ||||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | ||||
| Nicotine Activity on Dopaminergic Neurons | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Clinical pipeline report, company report or official report of the Pharmaceutical Research and Manufacturers of America (PhRMA) | |||
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