Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D07XCB
|
|||
| Former ID |
DNC009273
|
|||
| Drug Name |
1-Benzyl-3-phenylquinazoline-2,4(1H,3H)-dione
|
|||
| Synonyms |
CHEMBL520083; 1-Benzyl-3-phenylquinazoline-2,4(1H,3H)-dione; ZINC9926727; BDBM50251699
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H16N2O2
|
|||
| Canonical SMILES |
C1=CC=C(C=C1)CN2C3=CC=CC=C3C(=O)N(C2=O)C4=CC=CC=C4
|
|||
| InChI |
1S/C21H16N2O2/c24-20-18-13-7-8-14-19(18)22(15-16-9-3-1-4-10-16)21(25)23(20)17-11-5-2-6-12-17/h1-14H,15H2
|
|||
| InChIKey |
CUMHESHKEAHQDE-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Progesterone receptor (PGR) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Oocyte meiosis | |||
| Progesterone-mediated oocyte maturation | ||||
| Pathway Interaction Database | Cellular roles of Anthrax toxin | |||
| Reactome | Nuclear signaling by ERBB4 | |||
| Nuclear Receptor transcription pathway | ||||
| WikiPathways | Ovarian Infertility Genes | |||
| Signaling by ERBB4 | ||||
| Nuclear Receptors | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Progesterone receptor antagonists with a 3-phenylquinazoline-2,4-dione/2-phenylisoquinoline-1,3-dione skeleton. Bioorg Med Chem. 2008 Jul 15;16(14):7046-54. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.