Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07XLJ
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| Former ID |
DNC004818
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| Drug Name |
N*6*-Benzyl-quinazoline-2,4,6-triamine
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| Synonyms |
CHEMBL115474; N*6*-Benzyl-quinazoline-2,4,6-triamine; AC1LA5GO; ZINC5974540; BDBM50066486; N6-benzylquinazoline-2,4,6-triamine; 6-N-benzylquinazoline-2,4,6-triamine; 2,4-diamino-6-(benzylamino)quinazoline; 6-(Benzylamino)-2,4-quinazolinediamine
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H15N5
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| Canonical SMILES |
C1=CC=C(C=C1)CNC2=CC3=C(C=C2)N=C(N=C3N)N
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| InChI |
1S/C15H15N5/c16-14-12-8-11(6-7-13(12)19-15(17)20-14)18-9-10-4-2-1-3-5-10/h1-8,18H,9H2,(H4,16,17,19,20)
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| InChIKey |
PTWJNRZKGULCMJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Polypeptide deformylase (PDF) | Target Info | Inhibitor | [1] |
| Pathwhiz Pathway | Folate Metabolism | |||
| Pterine Biosynthesis | ||||
| Reactome | E2F mediated regulation of DNA replication | |||
| Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation | ||||
| Metabolism of folate and pterines | ||||
| G1/S-Specific Transcription | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | CoMFA and CoMSIA analyses of Pneumocystis carinii dihydrofolate reductase, Toxoplasma gondii dihydrofolate reductase, and rat liver dihydrofolate r... J Med Chem. 2005 Mar 10;48(5):1448-69. | |||
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