Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D07ZHE
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| Former ID |
DNC005108
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| Drug Name |
3-Nitro-benzenesulfonamide
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| Synonyms |
3-Nitrobenzenesulfonamide; 121-52-8; Benzenesulfonamide, 3-nitro-; m-Nitrobenzenesulfonamide; 3-Nitrobenzolesulfamide; m-Nitrobenzenesulphonamide; 3-nitrobenzenesulphonamide; 3-Nitro-benzenesulfonamide; Benzenesulfonamide, m-nitro-; 3-nitrobenzene-1-sulfonamide; CHEMBL367035; TXTQURPQLVHJRE-UHFFFAOYSA-N; EINECS 204-477-8; NSC 407487; m-nitrobenzolsulfonamid; 3-nitrophenylsulfonamide; AI3-50018; AC1Q1GYY; 3-nitro-benzenesulfonamid; m-Nitrobenzene sulfonamide; 3-nitrophenyl sulphonamide; 3-nitrobenzene sulfonamide; AC1L26XH
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C6H6N2O4S
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| Canonical SMILES |
C1=CC(=CC(=C1)S(=O)(=O)N)[N+](=O)[O-]
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| InChI |
1S/C6H6N2O4S/c7-13(11,12)6-3-1-2-5(4-6)8(9)10/h1-4H,(H2,7,11,12)
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| InChIKey |
TXTQURPQLVHJRE-UHFFFAOYSA-N
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| CAS Number |
CAS 121-52-8
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Carbonic anhydrase (CA) | Target Info | Inhibitor | [1] |
| Carbonic anhydrase II (CA-II) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Nitrogen metabolism | |||
| Proximal tubule bicarbonate reclamation | ||||
| Collecting duct acid secretion | ||||
| Gastric acid secretion | ||||
| Pancreatic secretion | ||||
| Bile secretion | ||||
| NetPath Pathway | IL4 Signaling Pathway | |||
| EGFR1 Signaling Pathway | ||||
| Reactome | Erythrocytes take up carbon dioxide and release oxygen | |||
| Erythrocytes take up oxygen and release carbon dioxide | ||||
| Reversible hydration of carbon dioxide | ||||
| WikiPathways | Reversible Hydration of Carbon Dioxide | |||
| Uptake of Carbon Dioxide and Release of Oxygen by Erythrocytes | ||||
| Uptake of Oxygen and Release of Carbon Dioxide by Erythrocytes | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Carbonic anhydrase inhibitors: inhibition of human cytosolic isozyme II and mitochondrial isozyme V with a series of benzene sulfonamide derivatives. Bioorg Med Chem Lett. 2004 Nov 15;14(22):5703-7. | |||
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