Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D08AGA
|
|||
Former ID |
DNC011822
|
|||
Drug Name |
3-((S)-Azetidin-2-yloxy)-5-iodo-pyridine
|
|||
Synonyms |
CHEMBL55138; 3-((S)-Azetidin-2-yloxy)-5-iodo-pyridine
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
|||
Formula |
C8H9IN2O
|
|||
Canonical SMILES |
C1CNC1OC2=CC(=CN=C2)I
|
|||
InChI |
1S/C8H9IN2O/c9-6-3-7(5-10-4-6)12-8-1-2-11-8/h3-5,8,11H,1-2H2/t8-/m0/s1
|
|||
InChIKey |
KSOZTGQWGPTPSV-QMMMGPOBSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Neuronal acetylcholine receptor alpha-2 (CHRNA2) | Target Info | Inhibitor | [1] |
KEGG Pathway | Neuroactive ligand-receptor interaction | |||
Panther Pathway | Nicotinic acetylcholine receptor signaling pathway | |||
Reactome | Highly calcium permeable postsynaptic nicotinic acetylcholine receptors | |||
Highly calcium permeable nicotinic acetylcholine receptors | ||||
WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell |
References | Top | |||
---|---|---|---|---|
REF 1 | Pharmacology of the agonist binding sites of rat neuronal nicotinic receptor subtypes expressed in HEK 293 cells. Bioorg Med Chem Lett. 2004 Apr 19;14(8):1845-8. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.