Drug Information
Drug General Information | Top | |||
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Drug ID |
D08BLV
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Former ID |
DNC012915
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Drug Name |
Isopropyl 3-(phenylthio)-1H-indole-2-carboxylate
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Synonyms |
SCHEMBL5812186
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C18H17NO2S
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Canonical SMILES |
CC(C)OC(=O)C1=C(C2=CC=CC=C2N1)SC3=CC=CC=C3
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InChI |
1S/C18H17NO2S/c1-12(2)21-18(20)16-17(22-13-8-4-3-5-9-13)14-10-6-7-11-15(14)19-16/h3-12,19H,1-2H3
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InChIKey |
CIEJDDRWESEPGF-UHFFFAOYSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Tubulin (TUB) | Target Info | Inhibitor | [1] |
Tubulin beta (TUBB) | Target Info | Inhibitor | [1] | |
KEGG Pathway | Phagosome | |||
Gap junction | ||||
Pathogenic Escherichia coli infection | ||||
NetPath Pathway | FSH Signaling Pathway | |||
TCR Signaling Pathway | ||||
EGFR1 Signaling Pathway | ||||
Panther Pathway | Cytoskeletal regulation by Rho GTPase | |||
Huntington disease | ||||
Reactome | Regulation of PLK1 Activity at G2/M Transition | |||
Loss of Nlp from mitotic centrosomes | ||||
Recruitment of mitotic centrosome proteins and complexes | ||||
Loss of proteins required for interphase microtubule organization?from the centrosome | ||||
Anchoring of the basal body to the plasma membrane | ||||
WikiPathways | Parkin-Ubiquitin Proteasomal System pathway | |||
Pathogenic Escherichia coli infection | ||||
Mitotic G2-G2/M phases |
References | Top | |||
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REF 1 | New arylthioindoles: potent inhibitors of tubulin polymerization. 2. Structure-activity relationships and molecular modeling studies. J Med Chem. 2006 Feb 9;49(3):947-54. |
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