Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08BSG
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| Former ID |
DNC003690
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| Drug Name |
IODOPROXYFAN
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| Synonyms |
Iodoproxyfan; CHEMBL19010; 152028-96-1; 5-[3-[(4-iodophenyl)methoxy]propyl]-1H-imidazole; 5-{3-[(4-iodophenyl)methoxy]propyl}-1H-imidazole; 4-[3-[(4-iodophenyl)methoxy]propyl]-3H-imidazole; AC1L31V0; SCHEMBL3089477; GTPL1253; 3-(1H-Imidazol-4-yl)propyl-(4-iodophenyl)methyl ether; BDBM22916; DTXSID30164942; ZINC5117186; PDSP2_000542; PDSP1_000544; L010934; 1H-Imidazole, 4-(3-((4-iodophenyl)methoxy)propyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C13H15IN2O
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| Canonical SMILES |
C1=CC(=CC=C1COCCCC2=CN=CN2)I
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| InChI |
1S/C13H15IN2O/c14-12-5-3-11(4-6-12)9-17-7-1-2-13-8-15-10-16-13/h3-6,8,10H,1-2,7,9H2,(H,15,16)
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| InChIKey |
DCQNAFOCXVCDLB-UHFFFAOYSA-N
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| CAS Number |
CAS 152028-96-1
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1253). | |||
| REF 2 | Different antagonist binding properties of human and rat histamine H3 receptors. Bioorg Med Chem Lett. 2001 Apr 9;11(7):951-4. | |||
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