Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08CYU
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| Former ID |
DNC003922
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| Drug Name |
2-Mercapto-pentanedioic acid
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| Synonyms |
Pentanedioic acid, 2-mercapto-; 2-Mercapto-pentanedioic acid; CHEMBL304885; 36303-63-6; 2-Mercaptoglutaric acid; SCHEMBL1204501; CTK1B0110; DTXSID20436307
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C5H8O4S
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| Canonical SMILES |
C(CC(=O)O)C(C(=O)O)S
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| InChI |
1S/C5H8O4S/c6-4(7)2-1-3(10)5(8)9/h3,10H,1-2H2,(H,6,7)(H,8,9)
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| InChIKey |
HWPIVZNZHAFMNA-UHFFFAOYSA-N
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| CAS Number |
CAS 36303-63-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Glutamate carboxypeptidase II (GCPII) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Metabolic pathways | ||||
| Vitamin digestion and absorption | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| TNFalpha Signaling Pathway | ||||
| Reactome | Amino acid synthesis and interconversion (transamination) | |||
| WikiPathways | One Carbon Metabolism | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and biological evaluation of thiol-based inhibitors of glutamate carboxypeptidase II: discovery of an orally active GCP II inhibitor. J Med Chem. 2003 May 8;46(10):1989-96. | |||
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