Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08HFA
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| Former ID |
DIB002635
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| Drug Name |
Y-27152
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| Synonyms |
Y-27152; 127408-30-4; N-(Benzyloxy)-N-((3S,4R)-6-cyano-3-hydroxy-2,2-dimethylchroman-4-yl)acetamide; N-[(3S,4R)-6-Cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)acetamide; NCGC00092304-01; AC1OCF4F; SCHEMBL8864736; CHEMBL1476996; CHEBI:92752; CTK4B5603; MolPort-003-983-713; HMS3268J07; ZINC3789145; Acetamide,N-[(3S,4R)-6-cyano-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-4-yl]-N-(phenylmethoxy)-; BN0549; AKOS022180527; AJ-45617; CC-31938; B6940; FT-0643069; C-35545; BRD-K42679050-001-01-3
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| Drug Type |
Small molecular drug
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| Indication | Angina pectoris [ICD-11: BA40; ICD-9: 413] | Discontinued in Phase 2 | [1] | |
| Company |
Mitsubishi Pharma Corp
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| Structure |
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Download2D MOL |
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| Formula |
C21H22N2O4
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| Canonical SMILES |
CC(=O)N(C1C(C(OC2=C1C=C(C=C2)C#N)(C)C)O)OCC3=CC=CC=C3
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| InChI |
1S/C21H22N2O4/c1-14(24)23(26-13-15-7-5-4-6-8-15)19-17-11-16(12-22)9-10-18(17)27-21(2,3)20(19)25/h4-11,19-20,25H,13H2,1-3H3/t19-,20+/m1/s1
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| InChIKey |
RHFUXPCCELGMFC-UXHICEINSA-N
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| CAS Number |
CAS 127408-30-4
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| PubChem Compound ID | ||||
| ChEBI ID |
CHEBI:92752
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800001561) | |||
| REF 2 | Pharmacokinetics and safety of a novel, long-acting, prodrug-type potassium channel opener, Y-27152, in healthy volunteers. J Clin Pharmacol. 1996 May;36(5):439-51. | |||
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