Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08HPU
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| Former ID |
DNC006347
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| Drug Name |
3-(3-methyl-3,4-dihydronaphthalen-2-yl)pyridine
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| Synonyms |
3-(3-methyl-3,4-dihydronaphthalen-2-yl)pyridine; Dihydronaphthalene 8; AC1O70HF; SCHEMBL4505804; BDBM8894
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H15N
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| Canonical SMILES |
CC1CC2=CC=CC=C2C=C1C3=CN=CC=C3
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| InChI |
1S/C16H15N/c1-12-9-13-5-2-3-6-14(13)10-16(12)15-7-4-8-17-11-15/h2-8,10-12H,9H2,1H3
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| InChIKey |
ARDWAGDGUKXSPH-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Aromatase (CYP19A1) | Target Info | Inhibitor | [1] |
| Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] | |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| Estradiol biosynthesis II | ||||
| Estradiol biosynthesis I | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Ovarian steroidogenesis | ||||
| NetPath Pathway | FSH Signaling Pathway | |||
| Panther Pathway | Androgen/estrogene/progesterone biosynthesis | |||
| Pathwhiz Pathway | Steroidogenesis | |||
| Androgen and Estrogen Metabolism | ||||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| Tryptophan metabolism | ||||
| Ovarian Infertility Genes | ||||
| FSH signaling pathway | ||||
| Integrated Breast Cancer Pathway | ||||
| Phase 1 - Functionalization of compounds | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and evaluation of heteroaryl-substituted dihydronaphthalenes and indenes: potent and selective inhibitors of aldosterone synthase (CYP11B... J Med Chem. 2006 Apr 6;49(7):2222-31. | |||
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