Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08IUE
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| Drug Name |
PMID25656651-Compound-37c
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| Drug Type |
Small molecular drug
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| Company |
NOVARTIS AG DODD, Stephanie Kay FURET, Pascal GROTZFELD, Robert Martin JAHNKE, Wolfgang JONES, Darryl Brynley MANLEY, Paul MARZINZIK, Andreas PELLE, Xavier Francois Andre SALEM, Bahaa SCHOEPFER, Joseph
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| Structure |
 |
Download2D MOL |
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| Formula |
C20H17ClF3N5O3
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| Canonical SMILES |
C1CN(CC1O)C2=C(C=C(C=N2)C(=O)NC3=CC=C(C=C3)OC(F)(F)Cl)C4=C(C=NN4)F
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| InChI |
1S/C20H17ClF3N5O3/c21-20(23,24)32-14-3-1-12(2-4-14)27-19(31)11-7-15(17-16(22)9-26-28-17)18(25-8-11)29-6-5-13(30)10-29/h1-4,7-9,13,30H,5-6,10H2,(H,26,28)(H,27,31)/t13-/m0/s1
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| InChIKey |
NAXNSUPRCUTVTP-ZDUSSCGKSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fusion protein Bcr-Abl (Bcr-Abl) | Target Info | Inhibitor | [1] |
| Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I) | Target Info | Inhibitor | [1] | |
| Target's Patent Info | Fusion protein Bcr-Abl (Bcr-Abl) | Target's Patent Info | [1] | |
| Fusion protein Bcr-Abl T315I mutant (Bcr-Abl T315I) | Target's Patent Info | [1] | ||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Bcr-Abl tyrosine kinase inhibitors: a patent review.Expert Opin Ther Pat. 2015 Apr;25(4):397-412. | |||
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