Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08JII
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| Drug Name |
Phenylpyrrolidinone derivative 1
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| Synonyms |
PMID27646439-Compound-10
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| Drug Type |
Small molecular drug
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| Company |
GLAXOSMITHKLINE INTELLECTUAL PROPERTY (NO.2) LIMITED
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| Structure |
 |
Download2D MOL |
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| Formula |
C23H19F3N6O2
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| Canonical SMILES |
CN1C=C(C2=C(N=CN=C21)N)C3=CC=C(C=C3)N4CCC(C4=O)(C5=NC(=CC=C5)C(F)(F)F)O
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| InChI |
1S/C23H19F3N6O2/c1-31-11-15(18-19(27)28-12-29-20(18)31)13-5-7-14(8-6-13)32-10-9-22(34,21(32)33)16-3-2-4-17(30-16)23(24,25)26/h2-8,11-12,34H,9-10H2,1H3,(H2,27,28,29)
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| InChIKey |
DHELRXCAKDZMKY-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | PRKR-like endoplasmic reticulum kinase (PERK) | Target Info | Inhibitor | [1] |
| Target's Patent Info | PRKR-like endoplasmic reticulum kinase (PERK) | Target's Patent Info | [1] | |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Protein kinase R(PKR)-like endoplasmic reticulum kinase (PERK) inhibitors: a patent review (2010-2015).Expert Opin Ther Pat. 2017 Jan;27(1):37-48. | |||
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