Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08KCW
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| Drug Name |
PMID27109571-Compound-37
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| Drug Type |
Small molecular drug
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| Structure |
 |
Download2D MOL |
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| Formula |
C21H20F3N3O4S
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| Canonical SMILES |
CC1=C(C(=C(S1)NC(=O)C2=C(C3CCC2CC3)C(=O)O)C4=NC(=NO4)C(F)(F)F)C5CC5
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| InChI |
1S/C21H20F3N3O4S/c1-8-12(9-2-3-9)15(17-26-20(27-31-17)21(22,23)24)18(32-8)25-16(28)13-10-4-6-11(7-5-10)14(13)19(29)30/h9-11H,2-7H2,1H3,(H,25,28)(H,29,30)
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| InChIKey |
HXCOCQVXJUKVAX-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fatty acid-binding protein (FABP) | Target Info | Inhibitor | [1] |
| Target's Patent Info | Fatty acid-binding protein (FABP) | Target's Patent Info | [1] | |
| BioCyc | Malate-aspartate shuttle | |||
| L-kynurenine degradation | ||||
| 4-hydroxyproline degradation | ||||
| KEGG Pathway | Alanine, aspartate and glutamate metabolism | |||
| Cysteine and methionine metabolism | ||||
| Arginine and proline metabolism | ||||
| Tyrosine metabolism | ||||
| Phenylalanine metabolism | ||||
| Phenylalanine, tyrosine and tryptophan biosynthesis | ||||
| Metabolic pathways | ||||
| Biosynthesis of antibiotics | ||||
| Carbon metabolism | ||||
| 2-Oxocarboxylic acid metabolism | ||||
| Biosynthesis of amino acids | ||||
| Fat digestion and absorption | ||||
| Panther Pathway | Asparagine and aspartate biosynthesis | |||
| Pathwhiz Pathway | Glutamate Metabolism | |||
| Malate-Aspartate Shuttle | ||||
| Urea Cycle | ||||
| Reactome | Gluconeogenesis | |||
| Amino acid synthesis and interconversion (transamination) | ||||
| WikiPathways | Glycolysis and Gluconeogenesis | |||
| Metabolism of amino acids and derivatives | ||||
| Metabolism of carbohydrates | ||||
| Alanine and aspartate metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Fatty acid binding protein (FABP) inhibitors: a patent review (2012-2015).Expert Opin Ther Pat. 2016 Jul;26(7):767-76. | |||
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