Drug Information
Drug General Information | Top | |||
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Drug ID |
D08KZJ
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Former ID |
DIB019070
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Drug Name |
CAY 10471
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Synonyms |
CAY10471; CAY-10471
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Drug Type |
Small molecular drug
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Indication | Allergy [ICD-11: 4A80-4A85; ICD-10: T78.4; ICD-9: 995.3] | Investigative | [1] | |
Company |
7TM Pharma A/S
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Structure |
Download2D MOL
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Formula |
C21H21FN2O4S
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Canonical SMILES |
CN(C1CCC2=C(C1)C3=CC=CC=C3N2CC(=O)O)S(=O)(=O)C4=CC=C(C=C4)F
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InChI |
1S/C21H21FN2O4S/c1-23(29(27,28)16-9-6-14(22)7-10-16)15-8-11-20-18(12-15)17-4-2-3-5-19(17)24(20)13-21(25)26/h2-7,9-10,15H,8,11-13H2,1H3,(H,25,26)
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InChIKey |
CANCTKXGRVNXFP-UHFFFAOYSA-N
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Prostaglandin D2 receptor 2 (PTGDR2) | Target Info | Agonist | [2] |
Reactome | Prostanoid ligand receptors | |||
G alpha (i) signalling events | ||||
WikiPathways | GPCRs, Class A Rhodopsin-like | |||
GPCR ligand binding | ||||
GPCR downstream signaling |
References | Top | |||
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REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 339). | |||
REF 2 | Minor structural modifications convert the dual TP/CRTH2 antagonist ramatroban into a highly selective and potent CRTH2 antagonist. J Med Chem. 2005 Feb 24;48(4):897-900. |
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