Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08LIF
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| Former ID |
DIB008074
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| Drug Name |
Propiram fumarate
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| Synonyms |
Algeril; Diramax; Dirame; Diramine; Diratab; Propiram; FBA-4503
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| Drug Type |
Small molecular drug
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| Indication | Cancer related pain [ICD-11: MG30; ICD-10: R52.1, R52.2] | Discontinued in Phase 3 | [1] | |
| Company |
Bayer AG
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| Structure |
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Download2D MOL |
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| Formula |
C20H29N3O5
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| Canonical SMILES |
CCC(=O)N(C1=CC=CC=N1)C(C)CN2CCCCC2.C(=CC(=O)O)C(=O)O
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| InChI |
1S/C16H25N3O.C4H4O4/c1-3-16(20)19(15-9-5-6-10-17-15)14(2)13-18-11-7-4-8-12-18;5-3(6)1-2-4(7)8/h5-6,9-10,14H,3-4,7-8,11-13H2,1-2H3;1-2H,(H,5,6)(H,7,8)/b;2-1+
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| InChIKey |
WQTLOZFMTGYQDX-WLHGVMLRSA-N
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| CAS Number |
CAS 13717-04-9
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Opioid receptor (OPR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800003460) | |||
| REF 2 | The relative analgesic efficacy of propiram fumarate, codeine, aspirin, and placebo in post-impaction dental pain. J Clin Pharmacol. 1984 Jan;24(1):35-42. | |||
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