Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08MNG
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| Former ID |
DNC006864
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| Drug Name |
C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine
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| Synonyms |
2CB-Ind; CHEMBL424890; 912342-23-5; C-(5-bromo-4,7-dimethoxyindan-1-yl)methylamine; DTXSID70582080; BDBM50194751; 1H-Indene-1-methanamine, 5-bromo-2,3-dihydro-4,7-dimethoxy-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C12H16BrNO2
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| Canonical SMILES |
COC1=CC(=C(C2=C1C(CC2)CN)OC)Br
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| InChI |
1S/C12H16BrNO2/c1-15-10-5-9(13)12(16-2)8-4-3-7(6-14)11(8)10/h5,7H,3-4,6,14H2,1-2H3
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| InChIKey |
HCLPGYNQMVSQIM-UHFFFAOYSA-N
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| CAS Number |
CAS 912342-23-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agoni... J Med Chem. 2006 Sep 21;49(19):5794-803. | |||
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