Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08MRN
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| Former ID |
DAP000506
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| Drug Name |
Hexylcaine
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| Synonyms |
Hexilcaina; Hexylcainum; Osmocaine; Hexylcaine [INN]; Cyclaine (TN); Hexilcaina [INN-Spanish]; Hexylcainum [INN-Latin]; Osmocaine (TN); (2-Cyclohexylamino-1-methylethyl) benzoate; 1-(Cyclohexylamino)-2-propanol benzoate (ester); 1-(cyclohexylamino)propan-2-yl benzoate; 2-Propanol, 1-(cyclohexylamino)-, benzoate (ester)
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| Drug Type |
Small molecular drug
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| Indication | Anaesthesia [ICD-11: 9A78.6; ICD-10: Y48.3] | Approved | [1] | |
| Therapeutic Class |
Anesthetics
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| Company |
Merck & Co
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| Structure |
 |
Download2D MOL |
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| Formula |
C16H23NO2
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| Canonical SMILES |
CC(CNC1CCCCC1)OC(=O)C2=CC=CC=C2
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| InChI |
1S/C16H23NO2/c1-13(12-17-15-10-6-3-7-11-15)19-16(18)14-8-4-2-5-9-14/h2,4-5,8-9,13,15,17H,3,6-7,10-12H2,1H3
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| InChIKey |
DKLKMKYDWHYZTD-UHFFFAOYSA-N
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| CAS Number |
CAS 532-77-4
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7846984, 8157802, 10525635, 11466816, 11467936, 11486571, 15020876, 29229231, 46506241, 47574639, 47721859, 47721860, 48170675, 49699365, 50022930, 50124095, 50897451, 57326453, 85788076, 103358344, 104324215, 117551385, 126408826, 134337799, 134976849, 136307715, 137008815, 160963819, 178103771, 179225807, 223442386, 224668640, 226420737, 249983020
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| ChEBI ID |
CHEBI:34791
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Voltage-gated sodium channel alpha Nav1.5 (SCN5A) | Target Info | Blocker | [2] |
| KEGG Pathway | Adrenergic signaling in cardiomyocytes | |||
| Pathwhiz Pathway | Muscle/Heart Contraction | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| WikiPathways | SIDS Susceptibility Pathways | |||
| Cardiac Progenitor Differentiation | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 | |||
| REF 2 | How many drug targets are there Nat Rev Drug Discov. 2006 Dec;5(12):993-6. | |||
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