Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08NLQ
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| Former ID |
DCL000867
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| Drug Name |
Licarbazepine
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| Synonyms |
GP 47779; GP-47779; (-)-10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide; 10,11-Dihydro-10-hydroxy-5H-dibenz(b,f)azepine-5-carboxamide; 10,11-Dihydro-10-hydroxycarbamazepine; 10-HYDROXY-CARBAMAZEPINE; 10-Hydroxy-10,11-dihydro-5H-dibenz(b,f)azepine-5-carboxamide; 10-Hydroxy-10,11-dihydrocarbamazepine; 10-Hydroxycarbamazepine; 10-Hydroxycarbazepine; 10-OH-Carbazepine; 5-hydroxy-5,6-dihydrobenzo[b][1]benzazepine-11-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Bipolar disorder [ICD-11: 6A60; ICD-10: F31] | Discontinued in Phase 3 | [1] | |
| Company |
Novartis
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| Structure |
 |
Download2D MOL |
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| Formula |
C15H14N2O2
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| Canonical SMILES |
C1C(C2=CC=CC=C2N(C3=CC=CC=C31)C(=O)N)O
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| InChI |
1S/C15H14N2O2/c16-15(19)17-12-7-3-1-5-10(12)9-14(18)11-6-2-4-8-13(11)17/h1-8,14,18H,9H2,(H2,16,19)
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| InChIKey |
BMPDWHIDQYTSHX-UHFFFAOYSA-N
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| CAS Number |
CAS 29331-92-8
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| PubChem Compound ID | ||||
| PubChem Substance ID |
9696, 7784957, 10236459, 15122329, 29296358, 49961418, 53786979, 57338774, 74832374, 91612621, 103096889, 103292732, 104179204, 104396686, 117569774, 123109974, 125823413, 127537463, 135070112, 137128961, 137237041, 139113422, 162261761, 162312777, 162831436, 163418503, 163850052, 164840168, 172866983, 179293331, 223395621, 223438646, 226745918, 237439165, 249582091, 249857730, 250071337, 250217218, 252070881, 252157593, 252237691, 252325768, 252419301, 252474827
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| ChEBI ID |
CHEBI:701
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Sodium channel unspecific (NaC) | Target Info | Blocker | [1] |
| KEGG Pathway | Dopaminergic synapse | |||
| Reactome | Interaction between L1 and Ankyrins | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Emerging drugs for bipolar disorder. Expert Opin Emerg Drugs. 2006 Nov;11(4):621-34. | |||
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