Drug Information
Drug General Information | Top | |||
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Drug ID |
D08NYZ
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Former ID |
DIB002269
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Drug Name |
ASM-024
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Indication | Asthma [ICD-11: CA23; ICD-10: J45, J45.8; ICD-9: 493] | Phase 2 | [1] | |
Company |
Asmacure Lt |e
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Structure |
Download2D MOL
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Formula |
C22H32N2O3S
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Canonical SMILES |
CC[N+]1(CCCN(CC1)C2=CC=CC=C2)CC.CC1=CC=C(C=C1)S(=O)(=O)[O-]
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InChI |
1S/C15H25N2.C7H8O3S/c1-3-17(4-2)13-8-11-16(12-14-17)15-9-6-5-7-10-15;1-6-2-4-7(5-3-6)11(8,9)10/h5-7,9-10H,3-4,8,11-14H2,1-2H3;2-5H,1H3,(H,8,9,10)/q+1;/p-1
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InChIKey |
PXRYYARWCNIUKT-UHFFFAOYSA-M
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CAS Number |
CAS 1609534-90-8
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Nicotinic acetylcholine receptor (nAChR) | Target Info | Agonist | [2] |
References | Top | |||
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REF 1 | ClinicalTrials.gov (NCT01190826) Safety, Tolerability and Clinical Activity of ASM-024 in Stable Moderate Asthma. U.S. National Institutes of Health. | |||
REF 2 | Effects of ASM-024, a modulator of acetylcholine receptor function, on airway responsiveness and allergen-induced responses in patients with mild asthma. Can Respir J. 2015 Jul-Aug;22(4):230-4. |
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