Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08SKX
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| Drug Name |
recAAT, PPL Therapeutics/Bayer
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| Synonyms |
AAT therapy, PPLTherapeutics/Bayer; alpha-1 antitrypsin, PPL Therapeutics/Bayer; rAAT, PPL
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cationic trypsinogen (PRSS1) | Target Info | Modulator | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Pancreatic secretion | ||||
| Protein digestion and absorption | ||||
| Influenza A | ||||
| Reactome | Activation of Matrix Metalloproteinases | |||
| Cobalamin (Cbl, vitamin B12) transport and metabolism | ||||
| WikiPathways | Activation of Matrix Metalloproteinases | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Reduction in neutrophil elastase concentration by recombinant alphal-antitrypsin (recAAT) does not alter bacterial loading in the sputum of cystic ... Br J Biomed Sci. 2004;61(3):146-7. | |||
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