Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08UWI
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| Former ID |
DNC011434
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| Drug Name |
2-Methyl-1-phenyl-2-pyridin-3-yl-propan-1-one
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| Synonyms |
87372-75-6; 2-Methyl-1-phenyl-2-(3-pyridinyl)-1-propanone; CHEMBL294460; 2-Mppp; 2-Methyl-1-phenyl-2-pyridin-3-yl-propan-1-one; AC1L37C5; SCHEMBL12260655; CTK5F8302; DTXSID50236312; ZINC5138212; BDBM50028170; KB-231336; 2-methyl-1-phenyl-2-pyridin-3-ylpropan-1-one
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C15H15NO
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| Canonical SMILES |
CC(C)(C1=CN=CC=C1)C(=O)C2=CC=CC=C2
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| InChI |
1S/C15H15NO/c1-15(2,13-9-6-10-16-11-13)14(17)12-7-4-3-5-8-12/h3-11H,1-2H3
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| InChIKey |
GWWVZTFGCNLAOV-UHFFFAOYSA-N
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| CAS Number |
CAS 87372-75-6
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Structure-activity relationship study of the inhibition of adrenal cortical 11 beta-hydroxylase by new metyrapone analogues. J Med Chem. 1984 Jan;27(1):15-9. | |||
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