Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08WHC
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| Former ID |
DNC010498
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| Drug Name |
(3-((1H-imidazol-1-yl)methyl)phenyl)methanol
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| Synonyms |
[3-(1H-Imidazol-1-ylmethyl)phenyl]methanol; 151055-79-7; CHEMBL597368; W-205714; [3-(imidazol-1-ylmethyl)phenyl]methanol; Benzenemethanol, 3-(1H-imidazol-1-ylmethyl)-; (3-((1H-imidazol-1-yl)methyl)phenyl)methanol; SCHEMBL3092795; DTXSID60439216; MolPort-000-143-255; ZX-AT016572; BDBM50307217; ZINC12370274; SBB090815; FCH921386; AKOS006343964; RP03595; [3-(imidazolylmethyl)phenyl]methan-1-ol; DB-063877; FT-0703495; Y7599; Benzenemethanol,3-(1H-imidazol-1-ylmethyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C11H12N2O
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| Canonical SMILES |
C1=CC(=CC(=C1)CO)CN2C=CN=C2
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| InChI |
1S/C11H12N2O/c14-8-11-3-1-2-10(6-11)7-13-5-4-12-9-13/h1-6,9,14H,7-8H2
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| InChIKey |
TXQZIKDWFOLTSC-UHFFFAOYSA-N
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| CAS Number |
CAS 151055-79-7
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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