Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08YGM
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| Former ID |
DIB020957
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| Drug Name |
SKF89976A
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| Synonyms |
SKF-89976A; SKF 89976A
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL
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| Formula |
C22H25NO2
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| Canonical SMILES |
C1CC(CN(C1)CCC=C(C2=CC=CC=C2)C3=CC=CC=C3)C(=O)O
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| InChI |
1S/C22H25NO2/c24-22(25)20-13-7-15-23(17-20)16-8-14-21(18-9-3-1-4-10-18)19-11-5-2-6-12-19/h1-6,9-12,14,20H,7-8,13,15-17H2,(H,24,25)
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| InChIKey |
TXQKSMSLZVKQBI-UHFFFAOYSA-N
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| CAS Number |
CAS 85375-85-5
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| PubChem Compound ID | ||||
| PubChem Substance ID |
4288389, 7980612, 10225398, 14802131, 26752062, 44423250, 47275553, 47869653, 48094543, 50065310, 50104717, 57335271, 76716537, 85788321, 90341296, 103088484, 103157819, 103216116, 103917590, 103978474, 104407359, 117547255, 124750274, 124881501, 124881502, 124881503, 129328769, 134223180, 135048450, 142472690, 162347663, 178101417, 179565946, 226972265
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| ChEBI ID |
CHEBI:91734
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA transporter GAT-1 (SLC6A1) | Target Info | Inhibitor | [2] |
| KEGG Pathway | GABAergic synapse | |||
| Reactome | Na+/Cl- dependent neurotransmitter transporters | |||
| WikiPathways | Monoamine Transport | |||
| NRF2 pathway | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4705). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 929). | |||
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