Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D08YGW
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| Former ID |
DNC010504
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| Drug Name |
1-Benzyl-5-phenyl-1H-imidazole
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| Synonyms |
1-benzyl-5-phenyl-1H-imidazole; 53704-79-3; 1-benzyl-5-phenylimidazole; SCHEMBL1501929; CHEMBL463582; CTK1G0360; BDBM24655; DTXSID30440036; AWZYHJQWJWUOHS-UHFFFAOYSA-N; AKOS015905520; 4-phenylimidazole (4-PI) derivative, 27; 1H-Imidazole, 5-phenyl-1-(phenylmethyl)-
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C16H14N2
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| Canonical SMILES |
C1=CC=C(C=C1)CN2C=NC=C2C3=CC=CC=C3
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| InChI |
1S/C16H14N2/c1-3-7-14(8-4-1)12-18-13-17-11-16(18)15-9-5-2-6-10-15/h1-11,13H,12H2
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| InChIKey |
AWZYHJQWJWUOHS-UHFFFAOYSA-N
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| CAS Number |
CAS 53704-79-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steroid 11-beta-hydroxylase (CYP11B1) | Target Info | Inhibitor | [1] |
| BioCyc | Superpathway of steroid hormone biosynthesis | |||
| Glucocorticoid biosynthesis | ||||
| Mineralocorticoid biosynthesis | ||||
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Metabolic pathways | ||||
| Pathwhiz Pathway | Steroidogenesis | |||
| Reactome | Glucocorticoid biosynthesis | |||
| Endogenous sterols | ||||
| WikiPathways | Metapathway biotransformation | |||
| Oxidation by Cytochrome P450 | ||||
| Metabolism of steroid hormones and vitamin D | ||||
| Corticotropin-releasing hormone | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis, biological evaluation, and molecular modeling of 1-benzyl-1H-imidazoles as selective inhibitors of aldosterone synthase (CYP11B2). J Med Chem. 2010 Feb 25;53(4):1712-25. | |||
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