Drug Information
Drug General Information | Top | |||
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Drug ID |
D08ZAX
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Former ID |
DIB003516
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Drug Name |
RS-93522
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Synonyms |
2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid methyl 2-[4-(2,3-dihydroxypropoxy)phenyl]ethyl diester; 2-[4-(2,3-Dihydroxypropoxy)phenyl]ethyl 2,6-dimethyl-3-(methoxycarbonyl)-4-(3-nitrophenyl)-1,4-dihydropyridine-5-carboxylate
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Drug Type |
Small molecular drug
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Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Terminated | [1] | |
Structure |
Download2D MOL |
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Formula |
C27H30N2O9
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Canonical SMILES |
CC1=C(C(C(=C(N1)C)C(=O)OCCC2=CC=C(C=C2)OCC(CO)O)C3=CC(=CC=C3)[N+](=O)[O-])C(=O)OC
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InChI |
1S/C27H30N2O9/c1-16-23(26(32)36-3)25(19-5-4-6-20(13-19)29(34)35)24(17(2)28-16)27(33)37-12-11-18-7-9-22(10-8-18)38-15-21(31)14-30/h4-10,13,21,25,28,30-31H,11-12,14-15H2,1-3H3
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InChIKey |
QLNAYPDWIWUVHP-UHFFFAOYSA-N
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CAS Number |
CAS 104060-12-0
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PubChem Compound ID | ||||
PubChem Substance ID |
Target and Pathway | Top | |||
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Target(s) | Calcium channel unspecific (CaC) | Target Info | Blocker | [2], [3] |
References | Top | |||
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REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002793) | |||
REF 2 | Intranasal delivery of RS-93522, a dihydropyridine-type calcium-channel antagonist. Pharm Res. 1991 Jan;8(1):134-5. | |||
REF 3 | Drugs@FDA. U.S. Food and Drug Administration. U.S. Department of Health & Human Services. 2015 |
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