Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D08ZHL
|
|||
| Former ID |
DCL000113
|
|||
| Drug Name |
FGF-1
|
|||
| Indication | Coronary heart disease [ICD-11: BA80.Z; ICD-9: 414] | Phase 2 | [1] | |
| Company |
CardioVascular BioTherape.
|
|||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Fibroblast growth factor receptor 1 (FGFR1) | Target Info | Binder | [2] |
| KEGG Pathway | MAPK signaling pathway | |||
| Ras signaling pathway | ||||
| Rap1 signaling pathway | ||||
| PI3K-Akt signaling pathway | ||||
| Adherens junction | ||||
| Signaling pathways regulating pluripotency of stem cells | ||||
| Regulation of actin cytoskeleton | ||||
| Pathways in cancer | ||||
| Proteoglycans in cancer | ||||
| Prostate cancer | ||||
| Melanoma | ||||
| Central carbon metabolism in cancer | ||||
| NetPath Pathway | TCR Signaling Pathway | |||
| Panther Pathway | Angiogenesis | |||
| FGF signaling pathway | ||||
| Pathway Interaction Database | Glypican 1 network | |||
| Syndecan-4-mediated signaling events | ||||
| N-cadherin signaling events | ||||
| FGF signaling pathway | ||||
| WikiPathways | Regulation of Actin Cytoskeleton | |||
| Endochondral Ossification | ||||
| MAPK Signaling Pathway | ||||
| Mesodermal Commitment Pathway | ||||
| Hair Follicle Development: Induction (Part 1 of 3) | ||||
| Integrated Pancreatic Cancer Pathway | ||||
| Signaling Pathways in Glioblastoma | ||||
| Neural Crest Differentiation | ||||
| Signaling by FGFR | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 4923). | |||
| REF 2 | Marimastat as maintenance therapy for patients with advanced gastric cancer: a randomised trial. Br J Cancer. 2002 Jun 17;86(12):1864-70. | |||
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