Drug Information
Drug General Information | Top | |||
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Drug ID |
D09BBW
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Former ID |
DIB003152
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Drug Name |
Sodium stibogluconate
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Synonyms |
Lenocta; Sodium stibogluconate (cancer); VQD-001; Sodium stibogluconate (cancer), Greenwich; Sodium stibogluconate (cancer), VioQuest
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Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C00-D48; ICD-9: 140-199, 210-229] | Phase 2 | [1], [2] | |
Company |
VioQuest
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Structure |
Download2D MOL |
Target and Pathway | Top | |||
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Target(s) | Leishmania DNA topoisomerase I (Leishm TOP1) | Target Info | Modulator | [1], [2] |
References | Top | |||
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REF 1 | Inhibition of Leishmania donovani promastigote DNA topoisomerase I and human monocyte DNA topoisomerases I and II by antimonial drugs and classical antitopoisomerase agents. J Parasitol. 2004 Oct;90(5):1155-62. | |||
REF 2 | Mode of action of pentavalent antimonials: specific inhibition of type I DNA topoisomerase of Leishmania donovani. Biochem Biophys Res Commun. 1988 Apr 29;152(2):605-11. |
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