Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09DDQ
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| Former ID |
DIB014502
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| Drug Name |
FUB-130
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| Synonyms |
FUB-132; FUB-250; FUB-465; FUB-86; UCL-1860; UCL-2065; UCL-2283; H3 antagonists, Bioprojet/Berlin Free University/INSERM/UCL
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| Drug Type |
Small molecular drug
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| Indication | Neurological disorder [ICD-11: 6B60] | Investigative | [1] | |
| Company |
BioProjet; Societe Civile de Recherche
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| Structure |
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Download2D MOL |
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| Formula |
C8H14N2O
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| Canonical SMILES |
CCOCCCC1=CN=CN1
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| InChI |
1S/C8H14N2O/c1-2-11-5-3-4-8-6-9-7-10-8/h6-7H,2-5H2,1H3,(H,9,10)
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| InChIKey |
RSHKAUMLIJVWFJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Antagonist | [2] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1260). | |||
| REF 2 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 264). | |||
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