Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09EXD
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| Former ID |
DAP000382
|
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| Drug Name |
Rituximab
|
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| Synonyms |
MAbThera (TN)
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|
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| Drug Type |
Antibody
|
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| Indication | Non-hodgkin lymphoma [ICD-11: 2B33.5; ICD-10: C85.9] | Approved | [1], [2] | |
| Haematological malignancy [ICD-11: 2B33.Y] | Phase 1 | [1], [2] | ||
| Therapeutic Class |
Anticancer Agents
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| Company |
Roche
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| PubChem Substance ID | ||||
| ADReCS Drug ID | BADD_D01953 | |||
| SuperDrug ATC ID |
L01XC02
|
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| Drug Resistance Mutation (DRM) | Top | |||
|---|---|---|---|---|
| DRM | DRM Info | |||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Leukocyte surface antigen Leu-16 (CD20) | Target Info | . | [3], [4] |
| KEGG Pathway | Hematopoietic cell lineage | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 6780). | |||
| REF 2 | Disease-modifying agents for multiple sclerosis: recent advances and future prospects. Drugs. 2008;68(17):2445-68. | |||
| REF 3 | [Contribution of radioimmunotherapy to the treatment of lymphoma]. Ann Pharm Fr. 2008 Nov-Dec;66(5-6):300-8. | |||
| REF 4 | Knockouts model the 100 best-selling drugs--will they model the next 100 Nat Rev Drug Discov. 2003 Jan;2(1):38-51. | |||
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