Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D09FZD
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| Former ID |
DNC013298
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| Drug Name |
N-(1-phenethylpiperidin-4-yl)-2-naphthamide
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| Synonyms |
CHEMBL388620; N-(1-phenethylpiperidin-4-yl)-2-naphthamide; MolPort-027-676-242; ZINC27939121; BDBM50203471; AKOS034266810; MCULE-8266051883; Z384294180; N-[1-(2-phenylethyl)piperidin-4-yl]naphthalene-2-carboxamide
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C24H26N2O
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| Canonical SMILES |
C1CN(CCC1NC(=O)C2=CC3=CC=CC=C3C=C2)CCC4=CC=CC=C4
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| InChI |
1S/C24H26N2O/c27-24(22-11-10-20-8-4-5-9-21(20)18-22)25-23-13-16-26(17-14-23)15-12-19-6-2-1-3-7-19/h1-11,18,23H,12-17H2,(H,25,27)
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| InChIKey |
JJJGQIPMMVJBLD-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | 5-HT 2A receptor (HTR2A) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Calcium signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Gap junction | ||||
| Serotonergic synapse | ||||
| Inflammatory mediator regulation of TRP channels | ||||
| Panther Pathway | 5HT2 type receptor mediated signaling pathway | |||
| Reactome | Serotonin receptors | |||
| G alpha (q) signalling events | ||||
| WikiPathways | Serotonin Receptor 2 and STAT3 Signaling | |||
| Serotonin Receptor 2 and ELK-SRF/GATA4 signaling | ||||
| SIDS Susceptibility Pathways | ||||
| Monoamine GPCRs | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| Gastrin-CREB signalling pathway via PKC and MAPK | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and in vitro binding studies of substituted piperidine naphthamides. Part I: Influence of the substitution on the basic nitrogen and the ... Bioorg Med Chem Lett. 2007 Mar 15;17(6):1565-9. | |||
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