Drug Information
Drug General Information | Top | |||
---|---|---|---|---|
Drug ID |
D09FZF
|
|||
Drug Name |
Diterpenoid derivative 1
|
|||
Synonyms |
PMID28454500-Compound-47
Click to Show/Hide
|
|||
Drug Type |
Small molecular drug
|
|||
Company |
BIOGEN MA INC
|
|||
Structure |
Download2D MOL |
|||
Formula |
C19H28O4
|
|||
Canonical SMILES |
CC1C2CCC(=C)C(C2(CCC1O)C)CC=C3C(COC3=O)O
|
|||
InChI |
1S/C19H28O4/c1-11-4-6-15-12(2)16(20)8-9-19(15,3)14(11)7-5-13-17(21)10-23-18(13)22/h5,12,14-17,20-21H,1,4,6-10H2,2-3H3/b13-5+/t12-,14-,15-,16-,17-,19+/m1/s1
|
|||
InChIKey |
VIGAUKOHNZARKF-YGQNBZPJSA-N
|
|||
PubChem Compound ID |
Target and Pathway | Top | |||
---|---|---|---|---|
Target(s) | Cysteines of Keap1 (KEAP1 Cysteines) | Target Info | Modulator | [1] |
Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target Info | Activator | [1] | |
Target's Patent Info | Cysteines of Keap1 (KEAP1 Cysteines) | Target's Patent Info | [1] | |
Nuclear factor erythroid 2-related factor 2 (Nrf2) | Target's Patent Info | [1] | ||
KEGG Pathway | Protein processing in endoplasmic reticulum | |||
NetPath Pathway | IL5 Signaling Pathway | |||
WikiPathways | Oxidative Stress | |||
Transcriptional activation by NRF2 | ||||
NRF2 pathway | ||||
Nuclear Receptors Meta-Pathway | ||||
Aryl Hydrocarbon Receptor Pathway | ||||
Mesodermal Commitment Pathway | ||||
Aryl Hydrocarbon Receptor | ||||
Quercetin and Nf-kB/ AP-1 Induced Cell Apoptosis | ||||
Arylhydrocarbon receptor (AhR) signaling pathway |
References | Top | |||
---|---|---|---|---|
REF 1 | Recent progress in the development of small molecule Nrf2 modulators: a patent review (2012-2016).Expert Opin Ther Pat. 2017 Jul;27(7):763-785. |
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.