Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09GHB
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| Former ID |
DIB011180
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| Drug Name |
RO-4987655
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| Synonyms |
CH-4987655; RO-04927350; MEK inhibitors (solid tumor), Roche
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| Drug Type |
Small molecular drug
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| Indication | Solid tumour/cancer [ICD-11: 2A00-2F9Z; ICD-10: C76-C80; ICD-9: 140-229] | Discontinued in Phase 1 | [1] | |
| Company |
F Hoffmann-La Roche Ltd
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| Structure |
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Download2D MOL |
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| Formula |
C20H19F3IN3O5
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| Canonical SMILES |
C1CC(=O)N(OC1)CC2=CC(=C(C(=C2F)F)NC3=C(C=C(C=C3)I)F)C(=O)NOCCO
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| InChI |
1S/C20H19F3IN3O5/c21-14-9-12(24)3-4-15(14)25-19-13(20(30)26-31-7-5-28)8-11(17(22)18(19)23)10-27-16(29)2-1-6-32-27/h3-4,8-9,25,28H,1-2,5-7,10H2,(H,26,30)
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| InChIKey |
FIMYFEGKMOCQKT-UHFFFAOYSA-N
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| CAS Number |
CAS 874101-00-5
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| PubChem Compound ID | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800028214) | |||
| REF 2 | MEK and the inhibitors: from bench to bedside. J Hematol Oncol. 2013; 6: 27. | |||
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