Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09GUJ
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| Drug Name |
Omadacycline
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| Synonyms |
UNII-090IP5RV8F; 090IP5RV8F; Omadacycline [USAN:INN]; Omadacycline (USAN); AC1NUY3H; Amadacycline methanesulfonate; SCHEMBL152
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| Indication | Acute bacterial skin infection [ICD-11: 1C41] | Approved | [1] | |
| Bacterial pneumonia [ICD-11: CA40.0] | Approved | [1] | ||
| Bacterial infection [ICD-11: 1A00-1C4Z; ICD-10: A00-B99] | Phase 3 | [2] | ||
| Company |
Paratek Pharmaceuticals
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| Structure |
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Download2D MOL |
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| Formula |
C29H40N4O7
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| Canonical SMILES |
CC(C)(C)CNCC1=CC(=C2CC3CC4C(C(=O)C(=C(C4(C(=O)C3=C(C2=C1O)O)O)O)C(=O)N)N(C)C)N(C)C
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| InChI |
1S/C29H40N4O7/c1-28(2,3)12-31-11-14-10-17(32(4)5)15-8-13-9-16-21(33(6)7)24(36)20(27(30)39)26(38)29(16,40)25(37)18(13)23(35)19(15)22(14)34/h10,13,16,21,31,34-35,38,40H,8-9,11-12H2,1-7H3,(H2,30,39)/t13-,16-,21-,29-/m0/s1
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| InChIKey |
VJYKVCURWJGLPG-IQZGDKDPSA-N
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| CAS Number |
CAS 389139-89-3
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Bacterial 30S ribosomal RNA (Bact 30S rRNA) | Target Info | Inhibitor | [1] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Omadacycline Enters the Ring: A New Antimicrobial Contender.Pharmacotherapy. 2018 Dec;38(12):1194-1204. | |||
| REF 2 | ClinicalTrials.gov (NCT00865280) Study the Safety and Efficacy of PTK 0796 in Patients With Complicated Skin and Skin Structure Infection (CSSSI). U.S. National Institutes of Health. | |||
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