Drug Information
Drug General Information | Top | |||
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Drug ID |
D09GZQ
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Former ID |
DNC006573
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Drug Name |
Ac-hPhe-Leu-Gly-LeuVSMe
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Synonyms |
CHEMBL209243; Ac-hPhe-Leu-Gly-LeuVSMe
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C28H44N4O6S
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Canonical SMILES |
CC(C)CC(C=CS(=O)(=O)C)NC(=O)CNC(=O)C(CC(C)C)NC(=O)C(CCC1=CC=CC=C1)NC(=O)C
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InChI |
1S/C28H44N4O6S/c1-19(2)16-23(14-15-39(6,37)38)31-26(34)18-29-27(35)25(17-20(3)4)32-28(36)24(30-21(5)33)13-12-22-10-8-7-9-11-22/h7-11,14-15,19-20,23-25H,12-13,16-18H2,1-6H3,(H,29,35)(H,30,33)(H,31,34)(H,32,36)/b15-14+/t23-,24+,25+/m1/s1
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InChIKey |
NYFDCVWCYDTELB-GNEZGTDISA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cathepsin S (CTSS) | Target Info | Inhibitor | [1] |
KEGG Pathway | Lysosome | |||
Phagosome | ||||
Antigen processing and presentation | ||||
Tuberculosis | ||||
NetPath Pathway | Leptin Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Reactome | Endosomal/Vacuolar pathway | |||
Degradation of the extracellular matrix | ||||
Trafficking and processing of endosomal TLR | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
MHC class II antigen presentation | ||||
WikiPathways | Class I MHC mediated antigen processing & presentation | |||
Trafficking and processing of endosomal TLR |
References | Top | |||
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REF 1 | Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and c... J Med Chem. 2006 May 18;49(10):2953-68. |
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