Drug Information
Drug General Information | Top | |||
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Drug ID |
D09IMK
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Former ID |
DNC006569
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Drug Name |
Cbz-Ile-t-ButylGln-Ala-LeuVSMe
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Synonyms |
CHEMBL438612; Cbz-Ile-t-ButylGln-Ala-LeuVSMe
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Drug Type |
Small molecular drug
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Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
Structure |
Download2D MOL |
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Formula |
C34H55N5O8S
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Canonical SMILES |
CCC(C)C(C(=O)NC(CCC(=O)NC(C)(C)C)C(=O)NC(C)C(=O)NC(CC(C)C)C=CS(=O)(=O)C)NC(=O)OCC1=CC=CC=C1
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InChI |
1S/C34H55N5O8S/c1-10-23(4)29(38-33(44)47-21-25-14-12-11-13-15-25)32(43)37-27(16-17-28(40)39-34(6,7)8)31(42)35-24(5)30(41)36-26(20-22(2)3)18-19-48(9,45)46/h11-15,18-19,22-24,26-27,29H,10,16-17,20-21H2,1-9H3,(H,35,42)(H,36,41)(H,37,43)(H,38,44)(H,39,40)/b19-18+/t23-,24-,26+,27-,29-/m0/s1
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InChIKey |
YIFPZVMURBGBNU-NHVLHDLVSA-N
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PubChem Compound ID |
Target and Pathway | Top | |||
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Target(s) | Cathepsin S (CTSS) | Target Info | Inhibitor | [1] |
KEGG Pathway | Lysosome | |||
Phagosome | ||||
Antigen processing and presentation | ||||
Tuberculosis | ||||
NetPath Pathway | Leptin Signaling Pathway | |||
IL2 Signaling Pathway | ||||
Reactome | Endosomal/Vacuolar pathway | |||
Degradation of the extracellular matrix | ||||
Trafficking and processing of endosomal TLR | ||||
Assembly of collagen fibrils and other multimeric structures | ||||
MHC class II antigen presentation | ||||
WikiPathways | Class I MHC mediated antigen processing & presentation | |||
Trafficking and processing of endosomal TLR |
References | Top | |||
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REF 1 | Optimization of subsite binding to the beta5 subunit of the human 20S proteasome using vinyl sulfones and 2-keto-1,3,4-oxadiazoles: syntheses and c... J Med Chem. 2006 May 18;49(10):2953-68. |
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