Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09KYR
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| Former ID |
DIB002103
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| Drug Name |
RP-49356
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| Synonyms |
Aprikalim; Aprim; Aprikalim); RP-52891
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| Drug Type |
Small molecular drug
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| Indication | Hypertension [ICD-11: BA00-BA04; ICD-9: 401] | Phase 2 | [1] | |
| Company |
Rhone-Poulenc SA
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| Structure |
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Download2D MOL |
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| Formula |
C12H16N2OS2
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| Canonical SMILES |
CNC(=S)C1(CCCCS1=O)C2=CN=CC=C2
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| InChI |
1S/C12H16N2OS2/c1-13-11(16)12(6-2-3-8-17(12)15)10-5-4-7-14-9-10/h4-5,7,9H,2-3,6,8H2,1H3,(H,13,16)/t12-,17?/m1/s1
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| InChIKey |
GKEMHVLBZNVZOI-MTATWXBHSA-N
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| CAS Number |
CAS 89544-10-5
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Potassium channel unspecific (KC) | Target Info | Opener | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800000232) | |||
| REF 2 | Effects of pinacidil, RP 49356 and nicorandil on ATP-sensitive potassium channels in insulin-secreting cells. Br J Pharmacol. 1990 Mar;99(3):487-92. | |||
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