Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09OTF
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| Former ID |
DIB000709
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| Drug Name |
ACEA-1031
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| Synonyms |
Glystatin 1000 series member (1031), ACEA; Glystatin 1000 series member (1031), CoCensys
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| Indication | Cerebrovascular ischaemia [ICD-11: 8B1Z; ICD-10: I67.8; ICD-9: 434.91] | Terminated | [1] | |
| Company |
Acea Pharmaceuticals Inc
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| Structure |
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Download2D MOL |
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| Formula |
C8H3Br2N3O4
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| Canonical SMILES |
C1=C2C(=C(C(=C1Br)Br)[N+](=O)[O-])NC(=O)C(=O)N2
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| InChI |
1S/C8H3Br2N3O4/c9-2-1-3-5(6(4(2)10)13(16)17)12-8(15)7(14)11-3/h1H,(H,11,14)(H,12,15)
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| InChIKey |
HPDZNXVZXICVSF-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | N-methyl-D-aspartate receptor (NMDAR) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800008256) | |||
| REF 2 | In vitro pharmacology of ACEA-1021 and ACEA-1031: systemically active quinoxalinediones with high affinity and selectivity for N-methyl-D-aspartate receptor glycine sites. Mol Pharmacol. 1995 Mar;47(3):568-81. | |||
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