Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09ROV
|
|||
| Former ID |
DNC001038
|
|||
| Drug Name |
Nortropinyl-arylsulfonylurea 3
|
|||
| Synonyms |
CHEMBL333727; BDBM50134335; Benzeneacetic acid (1alpha,5alpha)-8-[3-(4-chlorophenylsulfonyl)ureido]-8-azabicyclo[3.2.1]octane-3beta-yl ester; 8-[N-(4-chlorophenylsulfonamido)-carbonyl amino]-8-azabicyclo[3.2.1]oct-3-yl 2-phenylacetate
Click to Show/Hide
|
|||
| Drug Type |
Small molecular drug
|
|||
| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
||
| Formula |
C22H24ClN3O5S
|
|||
| Canonical SMILES |
C1CC2CC(CC1N2NC(=O)NS(=O)(=O)C3=CC=C(C=C3)Cl)OC(=O)CC4=CC=CC=C4
|
|||
| InChI |
1S/C22H24ClN3O5S/c23-16-6-10-20(11-7-16)32(29,30)25-22(28)24-26-17-8-9-18(26)14-19(13-17)31-21(27)12-15-4-2-1-3-5-15/h1-7,10-11,17-19H,8-9,12-14H2,(H2,24,25,28)/t17-,18+,19?
|
|||
| InChIKey |
JLAXGKPNMOZKMF-DFNIBXOVSA-N
|
|||
| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Steryl-sulfatase (STS) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Steroid hormone biosynthesis | |||
| Pathwhiz Pathway | Androgen and Estrogen Metabolism | |||
| Reactome | Glycosphingolipid metabolism | |||
| WikiPathways | Estrogen metabolism | |||
| Vitamin D Receptor Pathway | ||||
| Sphingolipid metabolism | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Nortropinyl-arylsulfonylureas as novel, reversible inhibitors of human steroid sulfatase. Bioorg Med Chem Lett. 2003 Nov 3;13(21):3673-7. | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.