Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09RWW
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| Former ID |
DNC013003
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| Drug Name |
3-cyclopentoxycarbonyl-6-ethyl-4-quinolone
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| Synonyms |
CHEMBL202724
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C17H19NO3
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| Canonical SMILES |
CCC1=CC2=C(C=C1)NC=C(C2=O)C(=O)OC3CCCC3
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| InChI |
1S/C17H19NO3/c1-2-11-7-8-15-13(9-11)16(19)14(10-18-15)17(20)21-12-5-3-4-6-12/h7-10,12H,2-6H2,1H3,(H,18,19)
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| InChIKey |
XLRFFZMGTKMUJJ-UHFFFAOYSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | GABA(A) receptor alpha-1 (GABRA1) | Target Info | Inhibitor | [1] |
| GABA(A) receptor beta-2 (GABRB2) | Target Info | Inhibitor | [1] | |
| GABA(A) receptor gamma-2 (GABRG2) | Target Info | Inhibitor | [1] | |
| Gamma-aminobutyric acid receptor (GAR) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Retrograde endocannabinoid signaling | ||||
| GABAergic synapse | ||||
| Morphine addiction | ||||
| Nicotine addiction | ||||
| Serotonergic synapse | ||||
| Reactome | Ligand-gated ion channel transport | |||
| GABA A receptor activation | ||||
| WikiPathways | Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell | |||
| Iron uptake and transport | ||||
| SIDS Susceptibility Pathways | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | 4-quinolone derivatives: high-affinity ligands at the benzodiazepine site of brain GABA A receptors. synthesis, pharmacology, and pharmacophore mod... J Med Chem. 2006 Apr 20;49(8):2526-33. | |||
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