Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D09SFH
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| Former ID |
DNC011405
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| Drug Name |
R-82150
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| Synonyms |
R 82150; R82150; NSC633810; 126320-77-2; CHEMBL46961; methyl(3-methylbut-2-enyl)[ ]thione; NSC-633810; AC1MHD28; SCHEMBL599870; BDBM1433; TIBO R82150; TIBO-R82150; DTXSID60155141; 4,5,6,7-tetrahydro-5-methylimidazo[4,5,1-jk][1,4]benzodiazepine-2(1H)-thione; (5R)-5beta-Methyl-6-(3-methyl-2-butenyl)-4,5,6,7-tetrahydroimidazo[4,5,1-jk][1,4]benzodiazepine-2(1H)-thione; (+)-S-4,6,7-Tetrahydro-5-methyl-6-(3-methyl-2-butenyl)-imidazo[4,5,1-jk][1,4]-benzodiazepin-2(1H)-thione
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| Drug Type |
Small molecular drug
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| Indication | Human immunodeficiency virus infection [ICD-11: 1C62; ICD-9: 279.3] | Discontinued in Phase 1 | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C16H21N3S
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| Canonical SMILES |
CC1CN2C3=C(CN1CC=C(C)C)C=CC=C3NC2=S
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| InChI |
1S/C16H21N3S/c1-11(2)7-8-18-10-13-5-4-6-14-15(13)19(9-12(18)3)16(20)17-14/h4-7,12H,8-10H2,1-3H3,(H,17,20)/t12-/m0/s1
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| InChIKey |
WTTIBCHOELPGFK-LBPRGKRZSA-N
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| CAS Number |
CAS 126320-77-2
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Human immunodeficiency virus Reverse transcriptase (HIV RT) | Target Info | Modulator | [2] |
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Trusted, scientifically sound profiles of drug programs, clinical trials, safety reports, and company deals, written by scientists. Springer. 2015. Adis Insight (drug id 800002478) | |||
| REF 2 | Kinetic interaction of human immunodeficiency virus type 1 reverse transcriptase with the antiviral tetrahydroimidazo[4,5,1-jk]-[1,4]-benzodiazepin... J Biol Chem. 1991 Aug 5;266(22):14232-6. | |||
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