Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A1UL
|
|||
| Former ID |
DIB011296
|
|||
| Drug Name |
RQ-00203078
|
|||
| Synonyms |
TRPM8 antagonists (pain), RaQualia Pharma
Click to Show/Hide
|
|||
| Indication | Neuropathic pain [ICD-11: 8E43.0] | Investigative | [1] | |
| Company |
RaQualia Pharma Inc
|
|||
| Structure |
 |
Download2D MOL |
||
| Formula |
C21H13ClF6N2O5S
|
|||
| Canonical SMILES |
C1=CC(=CC=C1CN(C2=C(C=C(C=N2)C(F)(F)F)Cl)S(=O)(=O)C3=CC=C(C=C3)C(=O)O)OC(F)(F)F
|
|||
| InChI |
1S/C21H13ClF6N2O5S/c22-17-9-14(20(23,24)25)10-29-18(17)30(11-12-1-5-15(6-2-12)35-21(26,27)28)36(33,34)16-7-3-13(4-8-16)19(31)32/h1-10H,11H2,(H,31,32)
|
|||
| InChIKey |
IJGQFZYYEHCCIZ-UHFFFAOYSA-N
|
|||
| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Long transient receptor potential channel 8 (TRPM8) | Target Info | Antagonist | [1] |
| KEGG Pathway | Inflammatory mediator regulation of TRP channels | |||
| Reactome | TRP channels | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Target id: 500). | |||
If You Find Any Error in Data or Bug in Web Service, Please Kindly Report It to Dr. Zhou and Dr. Zhang.