Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A2BC
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| Former ID |
DNC008364
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| Drug Name |
JWH-385
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| Synonyms |
JWH-385; CHEMBL259518
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|
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| Drug Type |
Small molecular drug
|
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
 |
Download2D MOL |
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| Formula |
C26H44O2
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| Canonical SMILES |
CCCCCCCCC(C)(C)C1=CC=C(C=C1)C2CC(CCC2CCCO)O
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| InChI |
1S/C26H44O2/c1-4-5-6-7-8-9-18-26(2,3)23-15-12-22(13-16-23)25-20-24(28)17-14-21(25)11-10-19-27/h12-13,15-16,21,24-25,27-28H,4-11,14,17-20H2,1-3H3/t21-,24-,25-/m1/s1
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| InChIKey |
ZWVZYXMEZOIWEQ-NQHRYMMQSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Cannabinoid receptor 1 (CB1) | Target Info | Inhibitor | [1] |
| Cannabinoid receptor 2 (CB2) | Target Info | Inhibitor | [1] | |
| KEGG Pathway | Rap1 signaling pathway | |||
| Neuroactive ligand-receptor interaction | ||||
| Retrograde endocannabinoid signaling | ||||
| Panther Pathway | Endogenous cannabinoid signaling | |||
| Pathway Interaction Database | N-cadherin signaling events | |||
| Reactome | Class A/1 (Rhodopsin-like receptors) | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCRs, Class A Rhodopsin-like | |||
| Small Ligand GPCRs | ||||
| BDNF signaling pathway | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Synthesis and pharmacology of 1-deoxy analogs of CP-47,497 and CP-55,940. Bioorg Med Chem. 2008 Jan 1;16(1):322-35. | |||
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