Drug Information
| Drug General Information | Top | |||
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| Drug ID |
D0A2WT
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| Former ID |
DNC011852
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| Drug Name |
4-((2R,3S)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole
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| Synonyms |
CHEMBL18735; Immepyr; 4-((2R,3S)-2-Methyl-pyrrolidin-3-yl)-1H-imidazole; 1H-Imidazole, 4-[(2R,3S)-2-methyl-3-pyrrolidinyl]-; BDBM50034708
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL |
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| Formula |
C8H13N3
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| Canonical SMILES |
CC1C(CCN1)C2=CN=CN2
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| InChI |
1S/C8H13N3/c1-6-7(2-3-10-6)8-4-9-5-11-8/h4-7,10H,2-3H2,1H3,(H,9,11)/t6-,7+/m1/s1
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| InChIKey |
FLOJCNYYPGNYBP-RQJHMYQMSA-N
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| PubChem Compound ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Inhibitor | [1] |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | Monoamine Transport | |||
| GPCRs, Class A Rhodopsin-like | ||||
| GPCR ligand binding | ||||
| GPCR downstream signaling | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | A novel pyrrolidine analog of histamine as a potent, highly selective histamine H3 receptor agonist. J Med Chem. 1995 May 12;38(10):1593-9. | |||
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