Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A4XL
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| Former ID |
DIB020470
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| Drug Name |
N-[3H]methylhistamine
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| Synonyms |
1-Methylhistamine; Tele-methylhistamine; 501-75-7; N1-Methylhistamine; N-Telle-methylhistamine; 2-(1-methyl-1H-imidazol-4-yl)ethanamine; 2-(1-methyl-1H-imidazol-4-yl)ethan-1-amine; 1-Methyl-1H-imidazole-4-ethanamine; 1H-Imidazole-4-ethanamine, 1-methyl-; 1-Methyl-4-histamine; UNII-KCB81T4EOF; N(sup 1)-Methylhistamine; NSC 66736; N-tele-Methylhistamine; CHEBI:29009; 1-methyl-4-(b-aminoethyl)imidazole; 1-Methyl-4-(2-aminoethyl)imidazole; KCB81T4EOF; 1-Methyl-4-(beta-aminoethyl)imidazole; BRN 0110757
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C6H11N3
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| Canonical SMILES |
CN1C=C(N=C1)CCN
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| InChI |
1S/C6H11N3/c1-9-4-6(2-3-7)8-5-9/h4-5H,2-3,7H2,1H3
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| InChIKey |
FHQDWPCFSJMNCT-UHFFFAOYSA-N
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| CAS Number |
CAS 501-75-7
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| PubChem Compound ID | ||||
| PubChem Substance ID |
7548, 111689, 5065180, 8145147, 8152280, 11111463, 15119885, 29222739, 47216971, 47810959, 48035337, 49979067, 50111134, 57321898, 76044006, 85209553, 90341373, 92298650, 103101425, 103173361, 104304019, 117477866, 117520177, 124749973, 124880726, 125676784, 126523660, 127848575, 132633463, 134223963, 134978378, 135650397, 135650399, 137099432, 141970489, 162860538, 164793246, 179235711, 198946623, 223789805, 226554786, 229808748, 249963036
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| ChEBI ID |
CHEBI:29009
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| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Histamine H3 receptor (H3R) | Target Info | Agonist | [2] |
| Histamine H4 receptor (H4R) | Target Info | Agonist | [2] | |
| KEGG Pathway | Neuroactive ligand-receptor interaction | |||
| Reactome | Histamine receptors | |||
| G alpha (i) signalling events | ||||
| WikiPathways | GPCR ligand binding | |||
| GPCR downstream signaling | ||||
| GPCRs, Other | ||||
| Monoamine Transport | ||||
| GPCRs, Class A Rhodopsin-like | ||||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | URL: http://www.guidetopharmacology.org Nucleic Acids Res. 2015 Oct 12. pii: gkv1037. The IUPHAR/BPS Guide to PHARMACOLOGY in 2016: towards curated quantitative interactions between 1300 protein targets and 6000 ligands. (Ligand id: 1241). | |||
| REF 2 | Cloning and pharmacological characterization of a fourth histamine receptor (H(4)) expressed in bone marrow. Mol Pharmacol. 2001 Mar;59(3):420-6. | |||
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