Drug Information
| Drug General Information | Top | |||
|---|---|---|---|---|
| Drug ID |
D0A6FZ
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| Former ID |
DIB020672
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| Drug Name |
peptide 18
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| Synonyms |
Ac-LLLLRVK-Amba
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| Drug Type |
Small molecular drug
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| Indication | Discovery agent [ICD-11: N.A.] | Investigative | [1] | |
| Structure |
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Download2D MOL
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| Formula |
C51H90N14O8
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| Canonical SMILES |
CC(C)CC(C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CC(C)C)C(=O)NC(CCCN=C(N)N)C(=O)NC(C(C)C)C(=O)NC(CCCCN)C(=O)NCC1=CC=C(C=C1)C(=N)N)NC(=O)C
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| InChI |
1S/C51H90N14O8/c1-28(2)23-38(59-33(11)66)46(69)62-40(25-30(5)6)48(71)64-41(26-31(7)8)49(72)63-39(24-29(3)4)47(70)60-37(16-14-22-57-51(55)56)45(68)65-42(32(9)10)50(73)61-36(15-12-13-21-52)44(67)58-27-34-17-19-35(20-18-34)43(53)54/h17-20,28-32,36-42H,12-16,21-27,52H2,1-11H3,(H3,53,54)(H,58,67)(H,59,66)(H,60,70)(H,61,73)(H,62,69)(H,63,72)(H,64,71)(H,65,68)(H4,55,56,57)/t36-,37-,38-,39-,40-,41-,42-/m0/s1
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| InChIKey |
UFNWIBYSOUCSGW-FVMQRRFMSA-N
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| PubChem Compound ID | ||||
| PubChem Substance ID | ||||
| Target and Pathway | Top | |||
|---|---|---|---|---|
| Target(s) | Dibasic-processing enzyme (Furin) | Target Info | Inhibitor | [1] |
| Neuroendocrine convertase 2 (PCSK2) | Target Info | Inhibitor | [1] | |
| Proprotein convertase subtilisin/kexin type 6 (PCSK6) | Target Info | Inhibitor | [1] | |
| Proprotein convertase subtilisin/kexin type 7 (PCSK7) | Target Info | Inhibitor | [1] | |
| NetPath Pathway | IL2 Signaling Pathway | |||
| Panther Pathway | Alzheimer disease-amyloid secretase pathway | |||
| Alzheimer disease-presenilin pathway | ||||
| Endothelin signaling pathway | ||||
| Pathway Interaction Database | Notch signaling pathway | |||
| p75(NTR)-mediated signaling | ||||
| HIF-1-alpha transcription factor network | ||||
| Glypican 3 network | ||||
| Reactome | Insulin processing | |||
| WikiPathways | Insulin Processing | |||
| References | Top | |||
|---|---|---|---|---|
| REF 1 | Design, synthesis, and structure-activity relationship studies of a potent PACE4 inhibitor. J Med Chem. 2014 Jan 9;57(1):98-109. | |||
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